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202-1257603

Does Your Child
Have CPP?

Central precocious puberty (CPP) is a condition where girls under 8 years old and boys under 9 begin puberty too early.1,2

3-Month Dosing

Ask Your Doctor About
3-Month Dosing

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

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Instant Savings

Get instant savings on
LUPRON DEPOT-PED

Your LUPRON DEPOT-PED Instant Savings Card can help you save on every prescription.

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Talk to a Nurse

Talk to a nurse live by phone
1-855-LUPRON-P

Get answers to your questions about LUPRON DEPOT-PED. Learn more.

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Treatment Options
for CPP

If your child has been diagnosed with central precocious puberty (CPP), effective treatment options are available.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

GO >
Instant Savings

Get instant savings on
LUPRON DEPOT-PED

Your LUPRON DEPOT-PED Instant Savings Card can help you save on every prescription.

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How LUPRON DEPOT-PED Works

How does LUPRON DEPOT-PED work to treat CPP?

LUPRON DEPOT-PED suppresses the production of hormones that cause puberty.2

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Treating CPP
with LUPRON
DEPOT-PED

You're sure to have lots of questions for your doctor before starting treatment. Learning what to expect with LUPRON DEPOT-PED treatment can help prepare you and your child for CPP therapy.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

GO >
Instant Savings

Get instant savings on
LUPRON DEPOT-PED

Your LUPRON DEPOT-PED Instant Savings Card can help you save on every prescription.

GO >
Progress Tracker

Progress tracker

This tool can help you track your child’s progress during treatment.

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Support & Savings
for LUPRON DEPOT-PED

You can talk to a registered nurse about your child’s LUPRON DEPOT-PED therapy and save money on each prescription.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

GO >
Talking With Your Physician

Questions for your child’s physician

Print these questions to help get your discussion going.

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Progress Tracker

Progress tracker

This tool can help you track your child’s progress during treatment.

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CPP OPTIONS TREATMENT SUPPORT
  • Do Not Take If

    Your child should not receive any formulation of LUPRON DEPOT-PED if he/she has experienced any type of allergic reaction to LUPRON DEPOT-PED or similar drugs.

    Females who are or may become pregnant should not receive any formulation of LUPRON DEPOT-PED.

    LUPRON DEPOT-PED is not for children under 2 years of age.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].

    202-653313

  • Before Starting

    Talk to your child's doctor about your child's medical history and all other medicines that your child takes.

    Convulsions have been observed in patients taking leuprolide acetate, including patients who have a history of seizures, epilepsy, or brain disorders (related to blood vessels, nerves, or tumors), and in patients who are taking medications that have been associated with convulsions. Convulsions have also been reported in patients without any of these conditions.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].

    202-653313

  • What to Expect

    During the first weeks of treatment, signs of puberty, such as vaginal bleeding, may occur. This is a common initial effect of the drug. Notify your child's doctor if signs/symptoms of puberty continue beyond the second month of treatment.

    After the injection, some pain and irritation is expected; however, if more severe symptoms occur or if any new, unusual, or worsened symptoms develop, contact your child's doctor.

    Your child's initial response to LUPRON DEPOT-PED should be monitored, as well as their continued response during treatment, as clinically needed.

    • If your child receives a 1-month injection, response is assessed 1–2 months after the initial injection.
    • If your child receives a 3-month injection, response is assessed 2–3 months after the initial injection and at month 6.
    • Height and bone age should be checked every 6–12 months in children using either formulation of LUPRON DEPOT-PED.

    It is important that you keep your child's doctor appointments and follow the prescribed injection schedule. Your child's pubertal development could begin again if injections are missed.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].

    202-653313

  • Side Effects

    The most common side effects with LUPRON DEPOT-PED and similar drugs are pain; acne; injection site reactions, including pain, swelling, and abscess; rash, including a painful rash with fever, blisters/sores, and facial swelling; vaginitis/vaginal bleeding/vaginal discharge; increased weight; altered mood; general pain; headache; fluctuating emotions; and hot flushes/sweating.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].

    202-653313

  • Helpful Resources

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

    If you cannot afford your medication, contact www.pparx.org or call the toll-free phone number (1-888-4PPANOW) for assistance.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].

    202-653313

Print Safety Facts

Use for LUPRON DEPOT-PED® (leuprolide acetate for depot suspension)

LUPRON DEPOT-PED 7.5 mg, 11.25 mg, and 15 mg for 1-month and 11.25 mg and 30 mg for 3-month administration are prescribed for the treatment of children with central precocious puberty (CPP).

More

Doctors may diagnose children with CPP when signs of sexual maturity begin to develop in girls under the age of 8 or boys under the age of 9. Your doctor should perform tests to rule out possible causes of CPP that would require different treatment (e.g., tumors).

LUPRON DEPOT-PED must be administered under the supervision of a physician.

Less
*Based on IMS Health, DDD™, and NDCHealth®, NDC Non-Retail™, September 2007, for the US market.

References: 1. Kaplowitz PB. Precocious puberty [eMedicine from WebMd Website]. Available at: http://www.emedicine.medscape.com/article/924002-print. Accessed March 29, 2011. 2. LUPRON DEPOT-PED [package insert]. 3. Data on file, AbbVie Inc.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org or call the toll-free number 1-888-477-2669.