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2016705-1912566

Does Your Child
Have CPP?1,2

Central precocious puberty (CPP) is a condition where girls under 8 years old and boys under 9 begin puberty too early.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing2

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

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Instant Savings

Get instant savings on
LUPRON DEPOT-PED

Your LUPRON DEPOT-PED Instant Savings Card can help you save on every prescription.

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Talk to a Nurse

Talk to a nurse live by phone
1-855-LUPRON-P

Get answers to your questions about LUPRON DEPOT-PED. Learn more.

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Treatment Options
for CPP

If your child has been diagnosed with central precocious puberty (CPP), effective treatment options are available.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing2

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

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Instant Savings

Get instant savings on
LUPRON DEPOT-PED

Your LUPRON DEPOT-PED Instant Savings Card can help you save on every prescription.

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How LUPRON DEPOT-PED Works

How does LUPRON DEPOT-PED work to treat CPP?2

LUPRON DEPOT-PED suppresses the production of hormones that cause puberty.

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Treating CPP
with LUPRON
DEPOT-PED2

You're sure to have lots of questions for your doctor before starting treatment. Learning what to expect with LUPRON DEPOT-PED treatment can help prepare you and your child for CPP therapy.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing2

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

GO >
Instant Savings

Get instant savings on
LUPRON DEPOT-PED

Your LUPRON DEPOT-PED Instant Savings Card can help you save on every prescription.

GO >
Progress Tracker

Progress Tracker

This tool can help you track your child’s progress during treatment.

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Support & Savings
for LUPRON
DEPOT-PED

You can talk to a registered nurse about your child’s LUPRON DEPOT-PED therapy and save money on each prescription.

3-Month Dosing

Ask Your Doctor About
3-Month Dosing2

3-month dosing is designed to offer less-frequent injections—only 4 injections per year for your child vs 12.

GO >
Talking With Your Physician

Questions for your child’s physician

Print these questions to help get your discussion going.

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Progress Tracker

Progress Tracker

This tool can help you track your child’s progress during treatment.

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CPP OPTIONS TREATMENT SUPPORT
  • Do Not Take If

    LUPRON DEPOT-PED should not be taken if your child is:

    • Allergic to GnRH, GnRH agonist medicines, or any ingredients in LUPRON DEPOT-PED.

    • Pregnant or becomes pregnant. LUPRON DEPOT-PED can cause birth defects or loss of the baby. If your child becomes pregnant, call your doctor.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].
  • Before Starting

    Before your child receives LUPRON DEPOT-PED, tell your doctor about all of your child’s medical conditions, including if they:

    • Have a history of mental (psychiatric) problems

    • Have a history of seizures

    • Have a history of epilepsy

    • Have a history of brain or brain vessel (cerebrovascular) problems or tumors

    • Are taking a medicine that has been connected to seizures, such as bupropion or selective serotonin reuptake inhibitors (SSRIs)

    • Are breastfeeding or plan to breastfeed. It is not known if LUPRON DEPOT-PED passes into the breast milk.

    Tell your doctor about all the medicines your child takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].
  • What to Expect

    What is the most important information I should know about LUPRON DEPOT-PED?

    • During the first 2 to 4 weeks of treatment, LUPRON DEPOT-PED can cause an increase in some hormones.
      During this time, you may notice more signs of puberty in your child, including vaginal bleeding. Call your doctor if these signs continue after the second month of treatment with LUPRON DEPOT-PED.

    • Some people taking gonadotropin-releasing hormone (GnRH) agonists like LUPRON DEPOT-PED have had new or worsened mental (psychiatric) problems. Mental (psychiatric) problems may include emotional symptoms such as:

      • Crying
      • Irritability
      • Restlessness (impatience)
      • Anger
      • Acting aggressive

    Call your child’s doctor right away if your child has any new or worsening mental symptoms or problems while taking LUPRON DEPOT-PED.

    • Some people taking GnRH agonists like LUPRON DEPOT-PED have had seizures. The risk of seizures may be higher in people who:

      • Have a history of seizures
      • Have a history of epilepsy
      • Have a history of brain or brain vessel (cerebrovascular) problems or tumors
      • Are taking a medicine that has been connected to seizures such as bupropion or selective serotonin reuptake inhibitors (SSRIs)

    Seizures have also happened in people who have not had any of these problems. Call your child’s doctor right away if your child has a seizure while taking LUPRON DEPOT-PED.

    • LUPRON DEPOT-PED is injected into your child’s muscle by a doctor or trained nurse.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].
  • Side Effects

    • The most common side effects of LUPRON DEPOT-PED received 1 time each month include:

      • Injection site reactions such as pain, swelling, and abscess
      • Weight gain
      • Pain throughout body
      • Headache
      • Acne or red, itchy rash and white scales (seborrhea)
      • Serious skin rash (erythema multiforme)
      • Mood changes
      • Swelling of vagina (vaginitis), vaginal bleeding, and vaginal discharge

    • The most common side effects of LUPRON DEPOT-PED received every 3 months include:

      • Injection site pain
      • Weight gain
      • Headache
      • Mood changes
      • Injection site swelling

    These are not all the possible side effects of LUPRON DEPOT-PED. Call your doctor for medical advice about side effects.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].
  • Helpful Resources

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

    If you cannot afford your medication, contact www.pparx.org.

    This is the most important information to know about LUPRON DEPOT-PED. For more information, talk to your doctor or healthcare provider.

    View the full Prescribing Information for LUPRON DEPOT-PED.

    Reference: LUPRON DEPOT-PED [package insert].
Print Safety Facts

Use for LUPRON DEPOT-PED® (leuprolide acetate for depot suspension)

LUPRON DEPOT-PED 7.5 mg, 11.25 mg, and 15 mg for 1-month and 11.25 mg and 30 mg for 3-month administration are prescribed for the treatment of children with central precocious puberty (CPP).

More

Doctors may diagnose children with CPP when signs of sexual maturity begin to develop in girls under the age of 8 or boys under the age of 9. Your doctor should perform tests to rule out possible causes of early puberty that would require different treatment (e.g., tumors).

It is not known if LUPRON DEPOT-PED is safe and effective in children under 2 years of age.

Less
*Based on IMS Health, DDD™, and NDCHealth®, NDC Non-Retail™.

References: 1. Precocious puberty. Mayo Clinic Web site. http://www.mayoclinic.com/health/precocious-puberty/DS00883. Accessed March 18, 2014. 2. LUPRON DEPOT-PED [package insert]. 3. Data on file, AbbVie Inc.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org or call the toll-free number 1-888-477-2669.

All photos are of models and not persons with central precocious puberty.

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