START AND STAYON LUPRON DEPOT-PEDTO CONTROL YOUR CHILD'S CENTRAL PRECOCIOUS PUBERTY (CPP)

Once you and your child’s doctor decide on treatment, the prescription will be sent to your insurance provider to determine costs. If you have any questions or concerns regarding coverage, Support PLUS can help. LUPRON DEPOT-PED is administered by a healthcare professional.

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Get ready to visit your child’s doctor and learn what to expect before, during, and after treatment.

TIPS FOR DOCTOR VISIT

Before Before

During During

After After

Help your child relax on the way to the doctor by playing a game or making up a song.

In the waiting room, having cards, a book, or something that can help distract your child can help ease some of the anxiety.

In the exam room, the nurse or medical assistant will prep your child for the injection.

The nurse may do an activity to help your child relax their muscles.

The injection site can vary between the upper arm, buttocks, or thigh to make the experience easier for your child.

After the injection, some pain and irritation at the site may occur. However, if more severe symptoms occur or if any new, unusual, or worsened symptoms develop, contact your child's doctor right away.

Helpful ways to distract your child if they are feeling anxious

Look out for signs that your child’s dose may need to change.

LOOK OUT FOR SIGNS

After your child starts therapy, they may first show more signs of puberty. Don’t worry! This is normal.

After the first few weeks, your child will stop producing the hormones causing their CPP and you should begin to see the signs of puberty slow down and then eventually stop.

Your healthcare team will assess your child for any side effects of treatment with LUPRON DEPOT-PED.

Month 1: After starting therapy, your child may first show increased signs and symptoms of CPP–this is normal.

It is a common initial effect of the drug to see an increase in the signs or symptoms of puberty during the first weeks of treatment. These symptoms should go away. If they continue beyond the second month, tell your child's doctor.

After month 1: After the first month, the hormones causing your child's CPP should be suppressed and you should begin to see the signs of puberty slow down and then eventually stop.

Call your child’s doctor immediately if:

Your daughter has menstrual bleeding that keeps going after the second month of treatment
Your child develops new or worsening mental (psychiatric) symptoms or problems
- Some people taking gonadotropin-releasing hormone (GnRH) agonists like LUPRON DEPOT-PED have had new or worsened mental (psychiatric) problems, such as:
  Crying
  
  Irritability
  Restlessness (impatience)
  
  Anger
  Acting aggressive
Your child has a seizure
- The risk of seizures may be higher in people who have a history of seizures, epilepsy, brain or brain vessel (cerebrovascular) problems or tumors, or in people who are taking a medicine that has been connected to seizures, such as bupropion or selective serotonin reuptake inhibitors (SSRIs)
- Seizures have also happened in people who have not had any of these problems
Your child has any of the following symptoms during treatment: headache, eye problems (including blurred vision, double vision, and decreased eyesight), eye pain, ringing in the ears, dizziness, or nausea
- These symptoms may be a sign of increased pressure in the fluid around the brain, which can happen in children taking GnRH agonist medicines, including LUPRON DEPOT-PED

See tips to help your child start and stay on track with treatment.

MONITORING TREATMENT

After you and your child’s doctor choose a treatment schedule for your child, it’s important to commit to it.

Make appointments for the year in advance. This helps you plan events around the appointments with plenty of notice.

Talk to your child's doctor about scheduling options. If it’s hard to get to appointments during regular office hours, tell your doctor. Some offices can work with your schedule.

Make visits a special time with your child. Plan a little something extra for the day or an adventure to go on to make it an event you and your child can look forward to.

You can help monitor your child's treatment progress along with your child’s doctor

You know your child best. If you see changes in your child, let your child's doctor know. It’s important to be aware of the possible side effects of LUPRON DEPOT-PED so you know what to look out for. The changes may be in your child’s body or their behavior. Keeping appointments gives you a good way to talk to your child's doctor about how your child is responding to treatment.

When is the right time to stop treatment?

Each child is different. Your child's pediatric endocrinologist will monitor your child’s progress during therapy. Talk to your child’s doctor about the best time for them to finish treatment.

When your child reaches the age when puberty should occur, the doctor will stop their treatment to allow their puberty to start back up again.

LUPRON DEPOT-PED paused early puberty in children with CPP. A group of patients who were treated with 1-month LUPRON DEPOT-PED were followed into adulthood. On average, they were taller than the height that was predicted for them when they were first diagnosed with CPP.

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Get the latest tips and information to help you and your child through the treatment journey.

Support PLUS & Resources

START AND STAYON LUPRON DEPOT-PEDTO CONTROL YOUR CHILD'S CENTRAL PRECOCIOUS PUBERTY (CPP)

TIPS FOR DOCTOR VISIT

LOOK OUT FOR SIGNS

After your child starts therapy, they may first show more signs of puberty. Don’t worry! This is normal.

MONITORING TREATMENT

You can help monitor your child's treatment progress along with your child’s doctor

When is the right time to stop treatment?

Find help understanding your insurance coverage

Need help talking about CPP?

Sign up for updates

Use for LUPRON DEPOT-PED^® (leuprolide acetate for depot suspension)

Important Safety Information for LUPRON DEPOT-PED

Important Safety Information

Important Safety Information

Important Safety Information

Important Safety Information

Use for LUPRON DEPOT-PED^® (leuprolide acetate for depot suspension)

Important Safety Information for LUPRON DEPOT-PED

START AND STAYON LUPRON DEPOT-PEDTO CONTROL YOUR CHILD'S CENTRAL PRECOCIOUS PUBERTY (CPP)

TIPS FOR DOCTOR VISIT

LOOK OUT FOR SIGNS

After your child starts therapy, they may first show more signs of puberty. Don’t worry! This is normal.

MONITORING TREATMENT

You can help monitor your child's treatment progress along with your child’s doctor

When is the right time to stop treatment?

Find help understanding your insurance coverage

Need help talking about CPP?

Sign up for updates

Use for LUPRON DEPOT-PED® (leuprolide acetate for depot suspension)

Important Safety Information for LUPRON DEPOT-PED

Important Safety Information

Important Safety Information

Important Safety Information

Important Safety Information

Use for LUPRON DEPOT-PED® (leuprolide acetate for depot suspension)

Important Safety Information for LUPRON DEPOT-PED

Use for LUPRON DEPOT-PED^® (leuprolide acetate for depot suspension)

Use for LUPRON DEPOT-PED^® (leuprolide acetate for depot suspension)