Once you and your child’s doctor decide on treatment, the prescription will be sent to your insurance provider to determine costs. If you have any questions or concerns regarding coverage, Support PLUS can help. LUPRON DEPOT-PED is administered by a healthcare professional.
Get ready to visit your child’s doctor and learn what to expect before, during, and after treatment.
The injection site can vary between the upper arm, buttocks, or thigh to make the experience easier for your child.
After the injection, some pain and irritation at the site may occur. However, if more severe symptoms occur or if any new, unusual, or worsened symptoms develop, contact your child's doctor right away.
Look out for signs that your child’s dose may need to change.
Your healthcare team will assess your child for any side effects of treatment with LUPRON DEPOT-PED.
Month 1: After starting therapy, your child may first show increased signs and symptoms of CPP–this is normal.
It is a common initial effect of the drug to see an increase in the signs or symptoms of puberty during the first weeks of treatment. These symptoms should go away. If they continue beyond the second month, tell your child's doctor.
After month 1: After the first month, the hormones causing your child's CPP should be suppressed and you should begin to see the signs of puberty slow down and then eventually stop.
Call your child’s doctor immediately if:
See tips to help your child start and stay on track with treatment.
Make appointments for the year in advance. This helps you plan events around the appointments with plenty of notice.
Talk to your child's doctor about scheduling options. If it’s hard to get to appointments during regular office hours, tell your doctor. Some offices can work with your schedule.
Make visits a special time with your child. Plan a little something extra for the day or an adventure to go on to make it an event you and your child can look forward to.
You know your child best. If you see changes in your child, let your child's doctor know. It’s important to be aware of the possible side effects of LUPRON DEPOT-PED so you know what to look out for. The changes may be in your child’s body or their behavior. Keeping appointments gives you a good way to talk to your child's doctor about how your child is responding to treatment.
Each child is different. Your child's pediatric endocrinologist will monitor your child’s progress during therapy. Talk to your child’s doctor about the best time for them to finish treatment.
When your child reaches the age when puberty should occur, the doctor will stop their treatment to allow their puberty to start back up again.
LUPRON DEPOT-PED paused early puberty in children with CPP. A group of patients who were treated with 1-month LUPRON DEPOT-PED were followed into adulthood. On average, they were taller than the height that was predicted for them when they were first diagnosed with CPP.
LUPRON DEPOT-PED 7.5 mg, 11.25 mg, and 15 mg for 1-month, 11.25 mg and 30 mg for 3-month, and 45 mg for 6-month administration are prescribed for the treatment of children with central precocious puberty (CPP).
It is not known if LUPRON DEPOT-PED is safe and effective in children less than 1 year old.
What is the most important information I should know about LUPRON DEPOT-PED?
Call your child's doctor right away if your child has any new or worsening mental symptoms or problems while taking LUPRON DEPOT-PED.
Seizures have also happened in people who have not had any of these problems. Call your child's doctor right away if your child has a seizure while taking LUPRON DEPOT-PED.
LUPRON DEPOT-PED should not be taken if your child is:
Before your child receives LUPRON DEPOT-PED, tell their doctor about all of your child's medical conditions, including if they:
Tell your child's doctor about all the medicines your child takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
How will your child receive LUPRON DEPOT-PED?
What are the possible side effects of LUPRON DEPOT-PED?
LUPRON DEPOT-PED may cause serious side effects. See “What is the most important information I should know about LUPRON DEPOT-PED?”
These are not all the possible side effects of LUPRON DEPOT-PED. Call your child’s doctor for medical advice about side effects.
This is the most important information to know about LUPRON DEPOT-PED. For more information, talk to your child’s doctor or healthcare provider.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
Please click here for full Prescribing Information.
US-LUPR-230025
How you act can also play a big role in helping reduce anxiety. If you’re anxious, your child will more likely be anxious. If you’re calm, your child will more likely be calm.
To reduce anxiety, you can tell jokes and make your child laugh by talking about funny things. Try not to talk about what the nurse is doing as they prepare the injection. Your child may become more distressed if you say sorry or tell them not to worry.
Talk to your child's doctor today about the #1* prescribed treatment for Central Precocious Puberty (CPP)
In a clinical study, the most common side effects of LUPRON DEPOT-PED received every 6 months included:
Please see additional Important Safety Information below.
Please see the full Prescribing Information.
*Data sourced as of February 2023.
†After the injection, some pain and/or irritation may occur. Call your child's doctor if these symptoms get worse or persist or if any new or unusual symptoms develop.
US-LUPR-230015
